Acute Pancreatitis: Etiology
Trauma
Pancreatic injury occurs more often after penetrating injury to the abdomen. Blunt injury to the abdomen or back may crush the gland across the spine, leading to a ductal injury.
Drugs
Common drugs associated with acute pancreatitis: Azathioprine, Sulfonamides, Tetracycline, Valproic acid, Methyldopa, Estrogens, Furosemide, 6-Mercaptopurine, 5-ASA, Corticosteroids, Octreotide
Less Common Causes
Bacterial causes: Mycoplasma pneumoniae, Salmonella, Campylobacter, and Mycobacterium tuberculosis.
Ascaris is a recognized cause of pancreatitis resulting from the migration of worms in and out of the duodenal papillae
Pancreatic injury occurs more often after penetrating injury to the abdomen. Blunt injury to the abdomen or back may crush the gland across the spine, leading to a ductal injury.
Drugs
Common drugs associated with acute pancreatitis: Azathioprine, Sulfonamides, Tetracycline, Valproic acid, Methyldopa, Estrogens, Furosemide, 6-Mercaptopurine, 5-ASA, Corticosteroids, Octreotide
Less Common Causes
- Infections
Bacterial causes: Mycoplasma pneumoniae, Salmonella, Campylobacter, and Mycobacterium tuberculosis.
Ascaris is a recognized cause of pancreatitis resulting from the migration of worms in and out of the duodenal papillae
- Hereditary Pancreatitis
- Hypercalcemia
- Developmental abnormalities of pancreas: Pancreatic divisum & annular pancreas
- Hypertriglyceridemia
- Tumours: Obstruction of pancreatic ductal system due to tumours can cause pancreatitis
- Toxins: organophosphate insecticides, scorpion and snake bites
- Surgical procedures: Abdominal surgeries or CABG may cause pancreatitis due to ischemia
- Autoimmune pancreatitis: very rare cause